Shukla was best known as the winner of the 13th season of hit reality TV show Bigg Boss, and as the lead actor in the Indian drama series Balika Vadhu.
A doctor at Mumbai’s Cooper Hospital confirmed the actor’s death to The Indian Express newspaper.
Shukla’s post-mortem examination has not begun yet, as police procedures are still ongoing, the paper reported.
Shukla is survived by his mother and two sisters.
Following the news, tributes began pouring in from fellow stars, fans and public figures in India.
The Family Man actor Manoj Bajpayee wrote on Twitter: “OMG!!! This is So Shocking!!! Words will fail to describe the shock and sense of loss of his near and dear ones !!! May he rest in peace !!! No yaar!!!!”
Indian cricketer Virender Sehwag wrote: “Another reminder of how fragile life is. Heartfelt condolences to #SiddharthShukla ‘s family and friends. Om Shanti”